ADD Medication


18
Aug 09

New ADHD Drug Vyvanse Review

I’ve only been taking it for one day, so this is just a first impression.

So far, no side effects, but I’m one of the lucky ones whose bodies tolerate medication pretty well.  The only Adderall side effect I ever had was dry mouth.  I drink so much coffee that constipation never had a chance :)

The one thing I have noticed about Vyvanse is that it doesn’t have the waking power of Adderall.  When I wake up tired and groggy, Adderall is a pretty quick boost of energy and wake-up power.  Vyvanse seems to be missing this.

I was pretty tired yesterday, and it was my day to go 100 MPH with my 3 year-old daughter, so no word yet on its impact on my usual ADD-ADHD symptoms

I’ll check in again about how Vyvanse is working after I’ve been taking it for a few days.

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17
Aug 09

Vyvanse Prescription ADD-ADHD Drug

add-prescription-graphic Since they stopped giving me antidepressants and anti-anxiety medications and realized that I had ADD-ADHD and not depression and anxiety, I have been taking Adderall generic AKA amphetamine salts.  Today, I start taking Vyvanse at the recommendation of my doc who says that some patients report a "smoother delivery."  Also, I only have to take one pill a day instead of pills 3 times a day.

The generic name of Vyvanse is lisdexamfetamine dimesylate.  I’m no chemist (but I did stay at a Holiday Inn Express last night) but I’m guessing that dexamfetamine part means that this drug bears a lot of resemblance to the old Dexatrim weight-loss pills that worked before they were forced to change their ingredients.

I am typically very suspicious of a doctor who tries to move a patient from an effective generic medication to a brand-name one that is for treating the same thing.  However, in this case, my doc said that I "could" try it if I wanted to because I often report "crashing" late in the evening, especially if I forget my afternoon dose of amphetamine salts.

According to the pharmacist, Vyvanse works by providing just the "most effective" of the amphetamine salts that are present in Adderall.  That salt is bound to another chemical which makes it absorb more slowly into the body.  Theoretically, this also makes Vyvanse harder to "abuse" because of the slow absorption.

Considering the only people who "abuse" Adderall and Ritalin in the first place are either students trying to study better or people trying to lose weight with Adderall, I’m not really sure that it matters how fast it absorbs so long as it still helps you concentrate (isn’t that the point).  And since one of the "common side effects" listed on my drug information sheet says weight loss, I’m guessing the people looking to drop a few pounds the easy way won’t mind either.

Ironically, Vyvanse might actually be cheaper for me even though it is still a brand name ADD drug under patent while my Adderall is a generic ADHD drug.

My insurance plan doesn’t cover Adderall or its generic for adults (anyone over 26 years old).  Apparently, some doctors will prescribe Adderall for their patients to lose weight, so instead of doing its job and monitoring abuse, the HMO just decided to not cover Adderall for anyone, including adults with ADD-ADHD who actually need it.

Vyvanse hasn’t hit the banned for fat reduction list, yet, so it is covered under the brand name co-pay, which ends up making it a bit cheaper.

Just for comparison purposes, my receipt from the Target Pharmacy lists the "Retail Value" of thirty 40 mg Vyvanse pills as $150.99.  It doesn’t show up on the Costco Prescription Price Checker, so I don’t know what it runs there.

Does Vyvanse work?

Is Vyvanse better than Adderall?

I guess I’ll find out soon enough.

I’ll keep you posted.


9
May 09

Non-Prescription ADD Treatment Options – St. John's Wart

My recent post on avoiding medical scams in the name of non-prescription ADD / ADHD treatment options, drew a heavy response, including a lot of people who were interested in what the non-prescription vitamin and supplement choices were that I referenced.

There are literally hundreds of vitamins or supplements that various people purport to have a positive affect on ADD behavior.  However, none of these treatments have received the kind of scientific study required to actually say that they do or do not work.  That isn’t surprising since there is no money in finding out that Vitamin X treats ADD symptoms better than Ritalin in children, getting funding for such research can be difficult.

(Incidentally, if you are a non-profit organization or scientific researcher or group that does ADD/ADHD research, and you would like some grant writing help, please feel free to contact me.  I’m a professional writer and I would love to help out by doing SOME pro bono work if it would bring some funding to your research. — Note: I’ve had one bad experience with a group in the past who thought that my offer to help gave them a free full-time grant writer.  I am willing to help, but I also have a family and a business to run, so please contact me with the right expectations in mind.  I will work hard to help get grants to fund this important research, but I can only do so with the flexibility my schedule allows.)

Some treatments only seem to have ADD benefits in children, while others only seem to work in adults.  And, most concerning of all, is the lack of data on side affects or other drug interactions.  So, make sure you do your own research and investigate all of the details.

I have done my best to list sources when I can remember them or re-find them.

St. John’s Wort For ADD / ADHD

St. John’s Wort is actually most commonly indicated for the treatment of low-grade depression. As such, it seems to help with certain ADD symptoms in some individuals, most likely because it treats some of the depression-like symptoms that occasionally manifest with certain types of ADHD. That being said, it does have a widespread following of ADDers who insist that it provides some relief for their symptoms.

St. John’s Wort has been shown to inhibit the reuptake of serotonin, dopamine, and norepinephrine.  This allows these neurotransmitters to build up to greater levels in the brain.  Depression is thought to be caused by low levels of these chemicals and that is why St. John’s Wort is effective in helping treat certain kinds of depression, according to research.

Theoretically, the same kind of mechanism may have something to do with ADD.  However, the research on that is still out.

What is known is that a large number of people with ADD/ADHD also show certain symptoms of depression.  Whether there is a correlation at a physical, biological, level, or if this there is just a correlation due to the lifelong burdens carried by some ADDers isn’t known.  However, if children, teens, and adults with ADHD do have some sort of depression in association with their ADD, then St. John’s Wort would help with the depression, which would provide an improved mental state overall, which could be misinterpreted as helping the ADD part of the issue.

Indeed, recent research from the National Institute of Health showed no improvement in ADD symptoms over a placebo in children and adolescents.

However, this was a very small study over a very small period of time.  Ironically, this is exactly the kind of research that gets dismissed by the medical establishment as non-conclusive when the study makes conclusions the other way around.  That is, if this study had found vast improvement, you could be sure that the researchers would conclude by saying that this was only a small sample and that further research was needed.  The fact that they don’t say that here, is disturbing to those of us who want to think that medical research gets a level playing field regardless of the outcome and whose profits might be hurt.

The study in question was 54 children aged 6 to 17 who were otherwise healthy and taking no other medications.  In standard scientific methodology half were giving St. Johns Wort and the other half were giving a placebo.  The two groups were generated randomly from the participants.  Then monitored for changes to inattentiveness and hyperactivity at 1, 2, 4, 6, and 8 weeks.

In other words, 27 children were tested to see how they responded to St. Johns Wort. The good news is that the study lasted 8 weeks, because the research on St. Johns Wort suggests that it takes several weeks to become effective.  But, the bad news is that at weeks 1 and 2, and maybe even week 4, there should not be any expected benefit.

The other bad news is that this study used the older weaker form of St. Johns Wort commonly sold in grocery stores and health food stores.  The newer form, called High Hyperforin contains 3% – 5% of hyperforin, versus the 0.14% used in the study.  However, since that form is relatively new and people have been claiming benefits since before it became available, this is still good research.

The really weird part of the study is that symptom improvement was noted to IMPROVE in BOTH groups!  While that lets the scientists conclude that there is no benefit of the supplement over the placebo, it raises an interesting question for those of us who actually care about those with ADD, namely, why did the symptoms improve for everyone?

Was it just that actually having some attention paid to their condition provided some help?  Was it that a new an interesting environment (where the observation took place) was enough to stimulate the minds of these children to help with symptoms?

Is The Criteria Too High?

Another interesting factor is that the researchers actively expected this outcome. They anticipated a 5-point reduction on the ADHD RS-IV total score in the placebo group!

Further, it was determined that in order to count as a “meaningful” improvement, the St. John’s Wort group would require a 13-point improvement on the same scale.

The ADHD RS-IV scale has 18 items. Each item is ranked from 0 to 3 with 0 being never or seldom, 1 being sometimes, 2 being often, and 3 being very often. In other words, the lowest possible score is 0 and the highest possible score is 54. So, for a meaningful result to be obtained, subjects needed to show a minimum of a 24% improvement! Considering that most people with ADD/ADHD aren’t necessarily looking for a result that would give a zero, and would be very happy to move down to a one on their major symptoms, this seems to be a very large requirement.

Obviously, more study is needed and there are interesting facts that should be looked at.

Should You Try St. Johns Wort for Your ADD?

Obviously, everyone has to make their own health decisions, and I am not a doctor, nor do I have any other certification or qualification, so take this a general knowledge only.

St. John’s Wort has been subjected to extensive study around the world, mostly in Europe.  During those studies no major immediate side effects have been reported. Indicating that St. John’s Wort can’t hurt, even if it doesn’t help.  This makes it a perfect treatment to try out and see if it can help you, even if it doesn’t meet the scientific criteria set out for clinical trials.

There is one area that is a concern and that is that St. John’s Wort does interact extensively with a wide array of medications.  In other words, St. John’s Worth is NOT the treatment for you to try if you currently take any prescription medication!

Talk to your doctor first to fully understand what affect St. John’s Wort might have on your medications BEFORE you try anything out.

Also, St. Jons Wort can be very stimulating to the brain.  That means that it can make it difficult for some people to sleep.  If you are taking St. Johns Wort, do it first thing in the morning. If you develop trouble sleeping, or it feels like your brain is “buzzing” then, cut back the dose or stop altogether.  You’ll be way better off with your usual ADD symptoms than you will be with long-term sleep deprivation.

Otherwise, if you are going to try alternative therapies, you could do a lot worse than St. John’s Wort.  Be careful, and listen to your body.  If it doesn’t feel right or you seem to have problems flare up, stop.

Also, remember that St. Johns Wort is not an instant-on treatment.  Depression patients report that it takes WEEKS for the herbal supplement to provide any noticeable improvement.  This is because inhibiting the re-uptake of neurotransmitters doesn’t mean you get the full smash right away, so if you are going to try it, don’t just take it for a week and decide it doesn’t work.

Pay attention to what you are buying.  Shifty supplement manufacturers and retailers want to capture your dollars no matter what, and they know that some people won’t pay certain prices.  That means that the lower concentration St. Johns will sell right next to the higher concentration supplements and no one will make that clear on the front facing label.  Turn the bottle around and make sure that you are getting the right amount that you have decided to start taking.  You’ll need a lot more of the 0.14% kind than you will of the 3% or 5% kind (and vice versa).

Good luck, and let me know how it goes for you by posting a comment or shooting me an email.

, , ADD/ADHD, Non-Prescription Treatment, ADD Mediction,

P.S.  If you noticed a couple of mispellings of key words like “Wort”, that is to allow those who search for information with mispelled words can still find this page.  That is also why I actively alternate between ADD, ADHD, and ADD/ADHD.


4
Apr 09

ADD ADHD Non-Medication Treatments

prescription-medicine ADD/ADHD can be a complicated thing to address.  Diagnosis is not standardized.  For one doctor, the bar for a diagnosis of ADD can be so high, he might diagnose one patient in 500.  For another, the bar might be so low that he simply answers, “Well lets try some medication,” at the smallest of issues or questions.  Even when the diagnosis is correct, ADHD doesn’t have the same symptoms for everyone.  There are three clinically defined variants of ADD, each with numerous variations in symptoms.

For these reasons, there can be a lot of confusion when it come to just who does or does not have ADD/ADHD and if they do, then what to do about it.  This concern is only heightened by the fact that we are talking about the brain which we regard not only as an important biological organ, but a very important part of exactly who we are.  Thus, some people worry about “tampering” with something so important.

Going Without Prescription Medication May Be Fine, But Beware Snakeoil ADD/ADHD Solutions

One of the biggest areas of disagreement and concern when it comes to treating ADD is the use of prescription drugs like Adderall, Ritalin, Concerta, and Vynasse, particularly when it comes to treating children with ADHD/ADD.  The issue is complex and I don’t pretend to have the answer for everyone.  Careful analysis of your particular situation is required to make such a decision.

However, there is one thing that is absolutely true without any debate.  There are a lot of slimy sleezeballs out there who want to exploit your concerns for their own enrichments.  Trust me, when I tell you, no matter how many times they write otherwise in their literature or websites, these people care about nothing other than their profits.

There are no miracle drugs, or magic herbal combinations, or vitamin supplements that work to treat ADD/ADHD in all people.

Just like there is no one prescription drug that works on all symptoms for all people, there is no non-prescription drug that does either.  People, face up to some reality.  No matter whether you take prescription stimulants or not, the undeniable fact is that these medications are not low impact drugs.  Between the heart warnings, and the increased suicide risks for teenagers, you should already know that these pills are not anyone’s first choice.   Even the pharmaceutical companies would love to replace their patent-expiring stimulant drugs with something else that they could charge outrageous prices on for the next 7 years.  If there was a clever little combination of B and K Vitamins that took care of everything, doctors, parents, patients, and holistic practioners would be racing to embrace it.

Instead, various unresearched, untested, unproven, concoctions are being sold to people with ADD looking for something to help.  Unfortunately, most of them do absolutely nothing but drain your pocketbook.

The Conspiracy Explanation Scam

The easiest way to continuously perpetrate a fraud is to insist that everyone who speaks against you is part of a vast conspiracy to hide the truth.  It’s even better if that fake conspiracy exists to “protect the profits” of big heartless corporations, or to “protect those in power”, or to “protect the system.”

You’ll notice that is very same excuse is used to explain why every single alternate ADD treatment is unknown and under the radar.  Only you, and the people who figured this all out, have discovered the truth. Everyone else is in on it. 

Think about it for two seconds.  Can it really be that there are 100 alternate treatments for ADD/ADHD and that ALL of them are subject to vast secretive conspiracies so effective that no medical group, legitimate research team, in this country or in ANY OTHER COUNTRY IN THE WHOLE WORLD, will stand up and speak the truth?  Really?  If someone actually could create and sustain such a  powerful conspiracy, can’t you think of MUCH more profitable ways to use it than to keep down Ritalin alternatives? 

Their reply will always be the same no matter how many facts you track down.

That’s what THEY want you to think.

Be careful, if you accept that non-sense here, you’re in for a long ride, because all the frauds use that line all the time.

Look at something like bovine growth hormone.  The FDA says its safe.  The label says its safe, but does is everybody in on the scam?  No!  Dozens of foreign countries ban it, hundreds of researchers have expressed doubts about its safety, there are dozens of peer-reviewed research studies about it.  There are even multiple companies making milk without BVG precisely because the government won’t ban it because it wants to protect the profits of heartless corporations.

Be smart.

Vitamins, Minerals, and Supplements

There are various claims that certain vitamins, minerals, or supplements may help certain sufferers of ADD/ADHD in certain circumstances.  That may or may not be true as there is no published peer-reviewed research on those claims.  That doesn’t mean it can’t help, and if you want to try other alternatives to prescription medication, then more power to you, just do it smart.

Any LEGITIMATE claim about the benefits of an alternate medical therapy of ANY KIND will not require you to purchase one specific proprietary product to get the benefits.  Neither chemistry, nor medicine work that way.  That’s why there are patents for drugs.  The same chemicals do the same thing, no matter what bottle they come out of.  So, if you read materials claiming that you MUST buy their product for any reason (quality, purity, secret blend), throw it in the recycle bin or close the webpage and move on.

If it is a legitimate alternative therapy, then any bottle of any vitamin or tree bark, or whatever on the shelf at Whole Foods should be just as good.

So, try the vitamins and other things.  Be smart.  I hope they work for you. 

The sad truth is that Adderall is a very powerful stimulant.  It was developed to treat narcolepsy, not ADD/ADHD.  Caffeine pills won’t even get you close unless you take the whole bottle.  Even then, you brain will filter it out differently and you’ll just get a stomach ache and a busted up liver.

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28
Jan 09

Adderall and Weight Loss

weight-loss Many people are interested in Adderall because it helps you lose weight.  At least, that’s what everyone hears thanks to sensational journalism designed to grab headlines.

The truth about Adderall, and the generic mixed amphetamine salts, is that it does not help you lose weight any more than drinking a bunch of coffee helps you lose weight.  Sure, it revs up your system a little bit, but the amount of extra metabolism one gets from taking Adderall wouldn’t be enough to overcome a single Oreo cookie.  Ephedrine burns off more fat by increasing your metabolism than Adderall does.

Losing Weight With Adderall

For SOME PEOPLE, definitely not all people, Adderall suppresses your appetite.  In other words, it makes it so you are not hungry.  In fact, some days, when I forget to take my afternoon dose, I remember because all of the sudden I’m very hungry.  Usually, I have to remind myself to eat lunch, so if I’m hungry in the afternoon I know something is up.

That means that if you have trouble losing weight because you find it hard to not eat too much when you are hungry, then Adderall MAY help.  Of course, that will only happen assuming you are one of the people who have their appetite suppressed by it.

But, if you have trouble losing weight because you eat things that you shouldn’t because they taste good, or because you go out with friends for lunch, or because you have a few beers each night, Adderall won’t be any help at all.  Another way to think about it is that if you are at a baseball game in the afternoon and you already ate lunch, so you really aren’t hungry, but you have a couple of hotdogs, some popcorn, and a few beers because you are at the ballpark and it’s part of the fun, Adderall isn’t going to help that at all.  Same thing goes for eating because you are nervous, depressed, stressed, or because you drive past a Dairy Queen on your way home every night.

In other words, Adderall does not burn extra calories, stop your body from absorbing fat, or make a big enough of a difference in your metabolism to make you lose weight no matter how much you eat.  All it can only make you less hungry.  So, if you only eat when you are hungry, the pounds will fall off, because you won’t be.

Otherwise, get the right meds for your ADD and find another way to lose weight.